The patented pheromone in the calming spray mimics a natural neonatal pheromone that reduces anxiety in a new or stressful environment. In scientific studies, this pheromone has been proven to modify both the behaviors and physiology brought on by stress. Clinical testing showed that the pheromone even reduced pets’ elevated heart rates when exposed to noises and activities that create anxiety. It is an excellent choice for temporary stressful situations such as trips to the veterinarian, groomer or new visitors. It helps make dogs and cats feel secure and safe at home and on-the-go.